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Are there instances when you use erythropoietin stimulating agents in patients with acute kidney injury requiring dialysis?

2 Answers
Mednet Member
Mednet Member
Nephrology · Rush Medical College

I cannot think of a reason to.

ESA resistance is common in sick patients and I think you are wasting the drug.

Please see reference: Aoun et al., PMID 35279078

'Erythropoietin treatment had no impact on transfusions, renal recovery or mortality in acute kidney injury patients with anemia."

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Mednet Member
Mednet Member
Nephrology · University Of California San Francisco Medical Center At Parnassus

I think we need more data and possibly some studies on this topic. most likely majority of patients with AKI in ICU won't respond to it. It also takes a long time for a response even in outpatients.

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