Are there scenarios in which you would advise using benzodiazepines for the treatment of hyperactive delirium?

The only situation that comes to mind is in patients who have active alcohol or benzodiazepine withdrawal as the etiology of their delirium. Outside of that, I do not use benzodiazepine therapy for delirium due to the risk of adverse effects (including prolonging the delirium) and lack of any data I am aware of showing efficacy.

In the setting of end-of-life care, I would consider using benzodiazepines, but only after I had used neuroleptics such as haloperidol or olanzapine, and I would be very cautious about it, starting at very low doses.