Are there situations in which elective nodal volumes may be reduced for T1/T2N0 anal SCC?
Is inguinal coverage always required?
Answer from: Radiation Oncologist at Community Practice
I have treated several elderly patients with small tumors using this low dose, limited field regimen. All did well.
Involved-Field, Low-Dose Chemoradiotherapy for Early-Stage Anal Carcinoma
Paul Hatfield, M.D., Ph.D., F.R.C.R., Rachel Cooper, M.D., M.Sc., F.R.C.R., David Sebag-Montefiore, M.D.,...
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Answer from: Radiation Oncologist at Academic Institution
There is another paper from France where they looked at the subsequent risk of inguinal nodes in untreated patients. I wish I could remember the reference, but I recall a 14% risk of failure in the nodes.
T1 tumors are not all the same. A well differentiated tumor at the anal ve...
Answer from: Radiation Oncologist at Academic Institution
I think treatment volume reduction for early anal cancer is worthy of a prospective study. However, there are several caveats. It would be important to have careful imaging to make sure one really is dealing with cN0 disease. I would recommmend FDG PET and careful review of imaging...