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Are triptans contraindicated for migraine treatment in patients with sickle cell disease?

What are alternative treatment options if so?
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Do you prescribe triptans to patients with sickle cell disease for migraine treatment?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Neurology · Stanford University
Answered on

Although triptans are not formally contraindicated in sickle cell disease, many SCD patients have silent cerebral infarcts and significant cerebrovascular vasculopathy, which are absolute contraindications to triptans. A thorough assessment for silent strokes, such as MRI/MRA, is recommended, and ex...

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