Are you requiring markers other than LTE4 to be elevated to diagnose MCAS?
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Mednet Member
Allergy & Immunology · Virginia Commonwealth University
The commercially available biomarkers to assess systemic mast cell activation in vivo include serum tryptase, N-methyl histamine (major metabolite of histamine), various forms of 11-beta-PGF2-alpha (PGD2 metabolite), and LTE4 (major metabolite of LTC4). The metabolites of these small molecules are m...