Based on NIAGARA data, do you now feel more comfortable offering cisplatin based chemotherapy to patients with impaired renal function?
Do you view creatinine clearance of 40 mL/min as the new cutoff for "cisplatin eligibility"?
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Based on NIAGARA, do you now feel more comfortable offering cisplatin-based chemo to patients with impaired renal function?
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1 Answer
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Medical Oncology · Mayo Clinic
Answered on
I agree, apart from the topline positive results in the intent-to-treat population, the preplanned subgroup analysis of lower GFR patients also appears to indicate a benefit, albeit somewhat less strong than traditional criteria. This adds to evidence from the phase 3 randomized VESPER trial of ddMV...
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