How would you approach treatment for a patient with positive C- ANCA/PR3 with sinus/nasal limited disease, but no renal or pulmonary involvement?
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What initial treatment would you choose for PR3-ANCA-positive sinonasal-limited GPA without renal or pulmonary involvement?
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1 Answer
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Rheumatology · Massachusetts General Hospital
Answered on · Updated on
The treatment of non-severe GPA varies amongst practitioners because of limited trial data and different practice patterns. 2021 ACR/VF guidelines conditionally recommend methotrexate and glucocorticoids. Rituximab would also be a reasonable option; therefore, I typically favor shared decision-makin...
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