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Can a lumpectomy boost be omitted in a cN0 triple negative breast cancer that has a complete response after neoadjuvant chemotherapy?

If planning standard fractionation, what factors would you consider in omitting a boost (ie age, LVSI, etc)?
3 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

At present we don't omit boost for triple negative even after pCR

We do participate in the study of exceptional responder to chemo where goal is to see if surgery can be omitted ( pts get adjuvant RT to breast plus boost without surgery)

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Radiation Oncology · Allegheny Health Network, Pittsburgh
Answered on

I would agree, we would not omit a boost in a cN0 trial negative patient. I would consider performing a SIB however.

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Radiation Oncology · Mayo Clinic Hospital
Answered on

I agree with the above. I recommend boost in this scenario.

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