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Radiation Oncology • Genitourinary Cancers
Can a PSA bounce be seen shortly after SBRT to prostate cancer oligometastases while on androgen deprivation therapy?
This patient's PSA rose from 0.2 to 2.0 at 3 months post-SBRT without PSMA avid lesions. How would you manage this: intensify treatment (such as with ARSI), follow with serial PSAs, or consider changing management in a different way?
Answer from: Radiation Oncologist at Community Practice
I have seen a PSA bounce if the PSA is done sooner than 3 months even while castrate. This is why I do not order a PSA until at least 3 months post any radiation - including to the primary or to metastatic sites.
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