Can radiation to the breast be given in the setting of prior radiation for Hodgkin's lymphoma?

Based on previous dose and volume (as most people are getting ISRT and between 20-30 Gy), either whole breast or partial breast RT are usually options. One concern I have is the increase IBTR which is most likely new primary in these patients because of prior RT exposure (akin to BRCA mutation). 

I have offered these patients breast conservation with breast TARGIT-IORT with success.

Here are some articles that include Hodgkin's patients who received mantle radiation and later developed a new breast cancer who then received TARGIT-IORT:

Chin et al., PMID 28894694 

Thangarajah et al., PMID 29335922 

The Europeans have been doing this for >10 years.

My patients are very grateful for this option as this article states:

Elfgen et al., PMID 32488732