Can the Fishbane reaction happen with an initial test dose of low molecular weight iron dextran, i.e., infed?
I.e., do you need prior sensitization, or is the test dose 'not enough' to cause the reaction? The patient immediately developed flushing, diaphoresis, SOB, emesis, and hypotension (90s/50s) with infed test dose without prior sensitization.
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How do you manage a suspected Fishbane reaction during IV iron infusion?
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Hematology · Georgetown University School of Medicine
Answered on
Yes, the fishbane reaction can occur with no prior exposure. This applies to any of the formulations. The reaction is more frequent with generic ferumoxytol, which should be avoided. Otherwise, the incidence is equally frequent. It is definitely not unique to iron dextran, as the question implies. W...
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