Allergy & Immunology

Mast Cell Disorders

Questions discussed in this category

What is the utility of remibrutinib or other tyrosine kinase inhibitors in MCAS?

Should a patient who has hereditary alpha tryptasemia and has experienced multiple anaphylactoid reactions be tested for a venom allergy and started on VIT if positive?

He cannot recall if he has been stung but if he did, it preceded his diagnosis and onset of symptoms, and he had no reaction. He has never been stung ...

2 Answers available

Do you use Xoliar as add-on treatment for hereditary alpha tryptasemia?

2 Answers available

Do you recommend patients try antihistamines such as oral ketotifen that are not approved in the US but are approved in the EU for MCAS if currently available formulations have not been effective?

1 Answer available

Does a patient with known systemic mastocytosis need a bone biopsy of lytic vertebral lesions to rule out other etiologies?

1 Answer available

Is there any role for immunosuppressive/immunomodulatory therapy used off label for mast cell activation syndrome besides omalizumab?

1 Answer available

Are you requiring markers other than LTE4 to be elevated to diagnose MCAS?

There has been new data to suggest LTE4 is not the best urinary marker of mast cell activation, so are you requiring other markers to be elevated to d...

1 Answer available

Do you favor 24 hour urinary metabolites over random urine collection when screening for MCAS?

1 Answer available

Do you diagnose MCAS if a patient is concurrently on drugs known to cause non-specific mast cell degranulation?

1 Answer available