Are you requiring markers other than LTE4 to be elevated to diagnose MCAS?

The commercially available biomarkers to assess systemic mast cell activation in vivo include serum tryptase, N-methyl histamine (major metabolite of histamine), various forms of 11-beta-PGF_2-alpha (PGD2 metabolite), and LTE4 (major metabolite of LTC4). The metabolites of these small molecules are m...