Gastroenterology

Pediatric Hematology/Oncology

Questions discussed in this category

What would be your next line of treatment for disease control in a pediatric patient with metastatic hepatocellular carcinoma in partial response after multiple therapies?

The patient already received PLADO+sorafenib, Y90, and Atezolizumab/Bevacizumab complicated by recurrent episodes of bleeding from esophageal varices....

3 Answers available

How do you counsel patients with acute intermittent porphyria when it comes to fasting for religious reasons?

Is there a way to determine a safe time period that allows a patient to fulfill their religious obligations or do you just recommend against fasting?

1 Answer available

How do you approach managing depression symptoms in patients who have had repeated high risk of bleeding?

When do you determine SSRI therapy is unsafe to pursue in such situations?

2 Answers available

Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

1 Answer available

Have you used oral vancomycin as prophylaxis for C difficile infection in patients admitted for allogeneic hematopoietic cell transplant?

2 Answers available

What is your approach to working up diarrhea in an immunocompromised patient?

1 Answer available

In a patient with recurrent fibrolamellar HCC a year after upfront resection (previously refused adjuvant therapy) with a solitary abdominal mass, would you offer neoadjuvant therapy to assess response?

Or offer resection followed by adjuvant therapy?

2 Answers available

How do you approach relapsed hepatocellular malignant neoplasm NOS after transplant in pediatric or AYA patients?

2 Answers available

How do you approach treatment of metastatic hepatocellular carcinoma in an adolescent?

Would you offer liver transplant in the setting of metastatic disease?

1 Answer available

Papers discussed in this category

Pharmacological research, 2016 Aug 10

Bleeding risk under selective serotonin reuptake inhibitor (SSRI) antidepressants: A meta-analysis of observational studies.

The Annals of pharmacotherapy, 2018 Aug 06

Clinical Management of Bleeding Risk With Antidepressants.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019-05-30

Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Aug 22

Effectiveness of Oral Vancomycin for Prevention of Healthcare Facility-Onset Clostridioides difficile Infection in Targeted Patients During Systemic Antibiotic Exposure.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Oct 23

Oral Vancomycin Prophylaxis for Clostridioides difficile in High-Risk Patients Receiving Systemic Antibiotics: What Exactly Are We Preventing?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Aug 22

Perils, Pitfalls, and Promise of Primary Prophylaxis for Clostridioides difficile Infection.

BMJ open, 2023 Sep 13

Evaluation of the effectiveness and safety of oral vancomycin versus placebo in the prevention of recurrence of infection in patients under systemic antibiotic therapy: a phase III, randomised, double-blind clinical trial.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019 Jun 27

Oral Vancomycin Prophylaxis as Secondary Prevention Against Clostridioides difficile Infection in the Hematopoietic Stem Cell Transplantation and Hematologic Malignancy Population.

The Journal of infection, 2011-11

Norovirus gastroenteritis successfully treated with nitazoxanide.

Alimentary pharmacology & therapeutics, 2006 Nov 15

Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.

Journal of tropical medicine, 2017 Feb 26

Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.

Gastroenterology

Pediatric Hematology/Oncology

Questions discussed in this category

Papers discussed in this category

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