Hematologic Malignancies

Pediatric Hematology

Questions discussed in this category

How would you manage aplastic anemia refractory to multiple agents?

Treated initially with hATG/CNI/TPO, but then relapsed. Subsequently treated with cyclosporine, danazol, ESA, and alemtuzumab, but still with pancytop...

1 Answer available

In an adult patient with asymptomatic, isolated neutropenia in whom you suspect a Duffy null phenotype, at what ANC or in what situations would you do a bone marrow to look for other etiologies of neutropenia?

1 Answer available

What is your standard diagnostic workup to confirm GVHD in a patient post-BMT with skin rash and jaundice?

2 Answers available

How will you use Pola-R-CHP in the frontline treatment of DLBCL?

Given the POLARIX study data presented at ASH 2021 and subsequent longer term follow up, will this replace R-CHOP as the standard of care therapy in y...

4 Answers available

What experience have you had with familial clustering of polycythemia vera?

Patient has a father and sister with both polycythemia vera with confirmed JAK2 V617F mutations. There is also suspicion for PV in a niece with pulmon...

1 Answer available

How would you approach post-operative VTE prophylaxis for renal transplant in patients with a prior history of provoked VTE?

Are there specific guidelines for managing this patient population?

1 Answer available

How would you manage a young patient with HL who develops HF (EF < 30%) after 4 cycles of A+AVD who obtained a PET2 CR?

2 Answers available

For T cell ALL treated in CR (without transplant), how often do you do BM biopsies as part of surveillance, and for how long?

What would you want community oncologists to know when following these patients? Are there any other special issues to follow especially in AYA?

1 Answer available

When patients develop headaches from luspatercept, do they tend to improve over time?

1 Answer available

What is the optimal age at which a patient with sickle cell disease should undergo allogeneic stem cell transplant?

2 Answers available

What are your top takeaways from ASH 2022?

8 Answers available

Do you do prophylactic LP/IT chemotherapy in high risk APML prior to starting consolidation?

1 Answer available

Which patients with acute promyelocytic leukemia do you consider maintenance after completing consolidation?

1 Answer available

What are contraindications for growth factors in patients with hematologic malignancies?

2 Answers available

In which patients with oncologic or hematologic disorders are you recommending a 3rd dose of mRNA COVID vaccine?

2 Answers available

How do you assess whether an early-stage Hodgkin's patient is unfavorable?

The unfavorable risk factors for stage I-II Classic Hodgkin's Lymphoma differ depending on the cooperative group (GHSG, EORTC, NCCN), which criteria d...

1 Answer available