How would you manage aplastic anemia refractory to multiple agents?
Treated initially with hATG/CNI/TPO, but then relapsed. Subsequently treated with cyclosporine, danazol, ESA, and alemtuzumab, but still with pancytopenia. Not a transplant candidate due to age mid 70s.
1 Answer
Mednet MemberInvited Expert
Hematology · Dana-Farber Cancer Institute
Answered on
If indeed the patient has been treated with all reasonable alternatives to BMT, the choices are 1) watch and wait with supportive care or 2) bone marrow transplantation. I understand the reluctance of transplanting someone in their 70s with aplastic anemia; however, we do this routinely in patients ...
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