Please select the option that best describes you:
Topics:
Hematologic Malignancies • Pediatric Hematology/Oncology • Aplastic Anemia • Hematology • Bone Marrow Failure • Pediatric Hematology • Benign Hematology
How would you manage aplastic anemia refractory to multiple agents?
Treated initially with hATG/CNI/TPO, but then relapsed. Subsequently treated with cyclosporine, danazol, ESA, and alemtuzumab, but still with pancytopenia. Not a transplant candidate due to age mid 70s.
Answer from: at Academic Institution
If indeed the patient has been treated with all reasonable alternatives to BMT, the choices are 1) watch and wait with supportive care or 2) bone marrow transplantation. I understand the reluctance of transplanting someone in their 70s with aplastic anemia; however, we do this routinely in patients ...
Sign in or Register to read more