Obstetrics & Gynecology

Benign Hematology

Questions discussed in this category

How do you approach delivery planning in patients with T1 vWD?

Do you routinely recommend a C-section over vaginal delivery? Induced vs spontaneous? If a C-section is needed, do you prefer general anesthesia over...

2 Answers available

For patients with a history of pregnancy loss, do you evaluate for PAI-1 polymorphisms as part of a thrombophilia workup?

If positive, do you anticoagulate for subsequent pregnancies?

1 Answer available

How often do you check weight and adjust anticoagulation dosing in pregnancy?

1 Answer available

How would you manage presumed gestational thrombocytopenia with moderate thrombocytopenia for delivery planning?

Platelet counts 50-80k in third trimester, with no obvious other underlying etiology on work up (vWD, TMA, no hx ITP), and no history of bleeding. How...

1 Answer available

What is your goal ferritin level in pregnancy?

ACOG 2021 practice guidelines use ferritin >30 ng/mL.

2 Answers available

In a patient with sickle cell disease on hydroxyurea who is planning to have a family, for how long should they be off the drug before trying to conceive?

1 Answer available

Papers discussed in this category

Journal of the National Medical Association, 2009-10

Exposure to hydroxyurea and pregnancy outcomes in patients with sickle cell anemia.

Blood,

Reproductive issues in sickle cell disease.

Trials, 2015-05-07

ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial.

Blood advances, 2018-11-27

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.

Lancet (London, England), 2022 Oct 28

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial.

Haemophilia : the official journal of the World Federation of Hemophilia, 2015-01

Postpartum von Willebrand factor levels in women with and without von Willebrand disease and implications for prophylaxis.

Blood Adv,

ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease.

Haemophilia : the official journal of the World Federation of Hemophilia, 2011 Sep 28

Changes in the levels of factor VIII and von Willebrand factor in the puerperium.

Journal of thrombosis and haemostasis : JTH, 2026 Jan 07

Higher-Dosed Clotting Factor Prophylaxis Fails to Reduce Postpartum Hemorrhage in Women With von Willebrand Disease: Findings from the Observational PRegnancy and Inherited bleeding DisordErS study (PRIDES).

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