Pulmonology

Non-Tuberculous Mycobacteria

Questions discussed in this category

Would you start treatment for MAC in a patient with nodular bronchiectatic disease who has demonstrated radiographic progression but remains asymptomatic and smear-negative?

3 Answers available

What is your preferred third antimicrobial agent for a patient with treatment-naive pulmonary MAC without cavitary disease and strict contraindications to utilization of rifampin or rifabutin?

5 Answers available

Is there a role for dual antibiotic treatment with ethambutol and macrolide only, as opposed to three-drug antibiotic therapy, in the treatment of treatment-naive pulmonary MAC without cavitary disease?

4 Answers available

Do you favor timely bronchoscopy for diagnostics over close surveillance in mildly symptomatic patients with CT findings suspicious for NTM infection who are not able to expectorate?

4 Answers available

Do add a macrolide for immunomodulatory effect in patients with macrolide-resistant M. abscessus?

2 Answers available

In which patients do you prefer daily standard three-drug therapy for non-cavitary pulmonary MAC as opposed to three times a week dosing?

2 Answers available

How long do you continue surveillance with imaging and sputum cultures in a patient with NTM with no indications for treatment?

3 Answers available

Are you using the microbial cell-free DNA “Karius” test to aid in the diagnosis of an atypical pulmonary infection such as PJP or NTM?

2 Answers available

Papers discussed in this category

Chest, 2023 Feb 17

Patient-Reported Symptom and Health-Related Quality-of-Life Validation and Responsiveness During the First 6 Months of Treatment for Mycobacterium avium Complex Pulmonary Disease.

The New England journal of medicine, 2014 Oct 01

Goal-directed resuscitation for patients with early septic shock.

The Journal of antimicrobial chemotherapy, 2022 May 29

Omadacycline efficacy in the hollow fibre system model of pulmonary Mycobacterium avium complex and potency at clinically attainable doses.

The Journal of infectious diseases, 2024 Aug 16

Oral β-Lactam Pairs for the Treatment of Mycobacterium avium Complex Pulmonary Disease.

The European respiratory journal, 2020 Jul 07

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.

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