Rheumatology

General Gastroenterology

Questions discussed in this category

Would you transition a patient with axial spondyloarthritis to a biologic if their axial symptoms were controlled with an NSAID, but they also required a PPI to control dyspepsia/GERD caused by the NSAID?

1 Answer available

How do you approach managing nausea and GI side effects when initiating methotrexate?

5 Answers available

How would you approach management of a patient with a medium-to-large vessel vasculitis who developed perforation of the stomach and colon on steroids and cyclophosphamide?

Vasculitis involving aorta, subclavian, common carotid, SMA, IMA, renal artery, and celiac artery.

1 Answer available

Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

1 Answer available

How do you approach GI prophylaxis (e.g., PPIs, H2 blockers) in patients on long-term NSAIDs?

1 Answer available

What is your treatment algorithm for management of retroperitoneal fibrosis that does not respond to high-dose glucocorticoids?

1 Answer available

When would you consider rituximab as induction therapy in IgG4-related disease?

4 Answers available

Would you intensify therapy in IgG4 related disease based solely on a persistently significantly elevated IgG4 level when all disease manifestations and inflammatory markers have normalized?

1 Answer available

How do you approach a patient with IgG4-related disease who has failed rituximab and mycophenolate and continues to rely on high-dose steroids?

The case I am considering involves a patient with biopsy-proven fibrosing dacryoadenitis.

1 Answer available

Papers discussed in this category

Annals of the rheumatic diseases, 2015-06

Rituximab for IgG4-related disease: a prospective, open-label trial.

Neth J Med,

The treatment outcomes in IgG4-related disease.

Medicine (Baltimore),

Therapeutic approach to IgG4-related disease: A systematic review.

The Journal of infection, 2011-11

Norovirus gastroenteritis successfully treated with nitazoxanide.

Alimentary pharmacology & therapeutics, 2006 Nov 15

Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.

Journal of tropical medicine, 2017 Feb 26

Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.

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