Rheumatology

Radiation Oncology   

Questions discussed in this category


Would you continue corticosteroid therapy even with a normalized serum IgG4 concentration?

In patients with bone metastases and osteoarthritis, if it is unclear if the pain is from cancer or OA, how do you decide on the radiation dose/fracti...

In which situations or patient populations do you find this useful? How is it sterilized?

Patient with active rheumatoid arthritis, on escalating dose of Rituxan and Methotrexate, also has antisynthetase syndrome and Hashimoto's thyroiditis...

If so, what dose-fractionation do you utilize? What other factors do you take into consideration?

There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?

The patient is on a dose of 22 mg of methotrexate weekly for severe rheumatoid arthritis. If you would discontinue the methotrexate, how long would y...

It's been 5+ years after the first course. If you decide to re-irradiate what dosing schema would you use?

The patient has notable lip lesions from her discoid lupus erythematosus

If you avoid parathyroid hormone-related protein analog drugs in patients with prior external beam radiation, what data is this based on?

How does a diagnosis of active RA inform your treatment approach for patients with breast cancer, if at all? 

Is there a risk of increased radioresistance or secondary malignancy (or conversely, toxicity) for patients on TNF inhibitors...

What non-pharmacological interventions do you recommend? Do you routinely prescribe prophylactic laxatives to patients initiating opioids? How do you ...

In a patient with early stage breast cancer that would otherwise require radiation, would you recommend treatment if the patient has active skin lupus...

Also, how would you handle immune modulators for rheumatoid arthritis during their treatment?

Would you require the rituxan to be held prior to radiation?  Would this matter if it was in the post-prostatectomy setting?

Are there any other medications, outside of anticoagulation, that would be considered absolute or relative contraindications?

Do you always stick with a conventional fracionation, or in some cases, are you comfortable hypofractionating? Do you ever use a wait and see approach...

Do you have any concern for increased toxicity when you treat a patient with radiation therapy who has an autoimmune disorder? (hypofractiationation v...


Papers discussed in this category


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997-07

Brachytherapy, 2011

Brachytherapy, 2011

JAMA Netw Open, 2021 Feb 01

Radiation oncology (London, England), 2012-02-16

Radiographics : a review publication of the Radiological Society of North America, Inc, 2004

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-03

The New England journal of medicine, 2015-07-16

Cancer,

Arthritis care & research, 2018-10

J Rheumatol, 2019 Apr 01

RMD Open,

Lancet Oncol., 2013-10-01

Int J Radiat Oncol Biol Phys, 2022 Apr 30

Int. J. Radiat. Oncol. Biol. Phys.,

The New England journal of medicine, 2019-06-13

Breast Care (Basel), 2019 Aug 16

JAMA, 2019 Apr 16

Head Neck, 2016 Mar 29

The Lancet. Oncology, 2017-05

The lancet. Diabetes & endocrinology, 2019 Aug 22

Rheumatology (Sunnyvale, Calif.), 2015 May 07

Annals of the rheumatic diseases, 2013 Jul 10

Journal of the Endocrine Society, 2022 Dec 02

Diagnostics (Basel, Switzerland), 2021 Apr 20