Surgical Oncology

NCI-CCC Breast Tumor Board Question

Questions discussed in this category

Would you recommend axillary lymph node dissection in a pre-menopausal woman with ER+ PR+ HER2- IDC, s/p lumpectomy and SLN with pT1c pN1 cM0 disease, where 2 sentinel nodes are positive for macrometastasis and 1 SN is positive for micrometastasis?

1 Answer available

In light of RxPonder results for postmenopausal women with early stage node positive HR+HER2- breast cancer, when is there a role for full axillary LN dissection to confirm degree of nodal involvement and when would sentinel LN evaluation be sufficient?

How would this affect adjuvant radiation plan in breast conservation therapy patients and mastectomy patients?

1 Answer available

Papers discussed in this category

JAMA, 2011-02-09

Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.

Annals of surgery, 2010-09

Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial.

Journal of reconstructive microsurgery, 2022 Feb 14

National Outcomes of Prophylactic Lymphovenous Bypass during Axillary Lymph Node Dissection.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2023 May 02

Prophylactic Lymphovenous Bypass at the Time of Axillary Lymph Node Dissection Decreases Rates of Lymphedema.

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