Would you recommend axillary lymph node dissection in a pre-menopausal woman with ER+ PR+ HER2- IDC, s/p lumpectomy and SLN with pT1c pN1 cM0 disease, where 2 sentinel nodes are positive for macrometastasis and 1 SN is positive for micrometastasis?

Topics: Breast Cancer • Medical Oncology • Surgical Oncology • NCI-CCC Tumor Board Question • University of Wisconsin • NCI-CCC Breast Tumor Board Question • Breast Cancer, Non-metastatic

Answer from: Medical Oncologist at Community Practice

ACOSOG Z0011 study showed that locoregional control, in patients with low to moderate axillary tumor burden treated with breast-conserving therapy and adjuvant systemic therapy, may not be improved by ALND after SLND compared to SLND alone. In ACOSOG Z0011, the detection of SN metastases was made ba...

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Medical Oncologist at Missouri Cancer Associates
There is also the SOUND clinical trial of SNB vs. ...

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