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Gastroenterology

Gastroenterology

Expert perspectives on IBD, liver disease, motility disorders, and GI diagnostic and therapeutic procedures.

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What therapies have you found most effective for JAK-induced/associated acne (JAKcne)?

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Dermatology · Johns Hopkins Timeshare Practice

Doxy will work quickly and is pretty safe. If all goes well, you can taper the dose of the oral antibiotic and use topical agents.

How would you approach endoscopic diagnosis and treatment of an area of visible nodularity concerning for cancer within long segment Barrett’s esophagus?

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Gastroenterology · University of Arizona

I would begin by careful inspection of the Barrett's (BE) mucosa under HD-white light and narrow band imaging after washing off the surface mucus. I would evaluate the entire BE segment for nodules, ulcers, irregularities in pit-pattern and focal changes in vascular pattern, raising suspicion for in...

Would you pursue a colonoscopy for a patient in their 20s with constipation and rectal bleeding if they had a first-degree relative who died young from a "carcinoid tumor"?

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Hospital Medicine · Temple University Hospital

Carcinoid tumor is relatively uncommon in someone who is relatively healthy and young. I would make sure to consider all the more common diagnoses and workup before considering carcinoid tumor. Moreover, carcinoid tumor is associated with diarrhea rather than constipation. Neuroendocrine tumor of th...

Do you obtain liver biopsy to confirm the diagnosis of cirrhosis if cirrhotic liver morphology is noted on imaging?

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Hepatology · UCLA

This question touches upon two interesting trends: 1) There is an increasing trend in Radiology to report "cirrhotic liver morphology" in the "Impressions" section. When you then review the Body of the report, often these cases are noted to only have a heterogeneous appearing liver with surface nodu...

What is your preferred first-line regimen to treat a severe or fulminant C difficile infection?

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Gastroenterology · Beitman Robert G Office

IV vancomycin and PO Flagyl are the easiest combination to get for a hospitalized patient. I’ve had much experience with this, and it works very well. IV vancomycin and PO Flagyl as initial treatments in the hospital is my preference. This is before I go onto stronger drugs, with those requiring al...

How do you approach using fecal microbiota therapy for recurrent Clostridioides difficile infection in immunocompromised patients?

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Infectious Disease · Johns Hopkins University

We generally do not do the single donor FMT via colonoscopy, that was popular 5-10 years ago. We do offer both the oral and enema-based products, with a slight preference for the oral-based product due to ease of use.

How long do you recommend waiting after variceal bleeding and banding before a transesophageal echocardiogram can be performed safely?

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Hepatology · UCLA

In the exact wording of this question, the scenario that is being presented is that the patient has had a variceal hemorrhage (VH) recently and urgent banding has already been performed to stop the VH (so that the concern would be of the TEE probe knocking off a band that is actively treating an eso...

What is your preferred screening tool for colon cancer in an average-risk patient?

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Primary Care · Duke University

For their first time screening, I universally recommend a colonoscopy (in the absence of contraindications or social barriers) to evaluate for polyps, followed in 5-10 years by a yearly FIT or Cologuard every three years (unless the patient has a strong preference for a repeat colonoscopy). Repeat c...

Do you recommend restarting GLP-1RA after bariatric surgery if they tolerated it before the surgery?

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Hospital Medicine · Emory University Hospital

While there are no clear recommendations on whether/when to resume GLP-1 RA after bariatric surgery, current 2025 guideline statements (ASMBS, ADA, AACE, Obesity Society) and expert consensus documents suggest the following approach: Hold GLP-1RA in the acute perioperative period. For daily-dosed ...

How long do you typically treat patients with phentermine for weight loss and what clinical markers do you follow?

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Endocrinology · Tufts Medical Center Physicians Organization

Phentermine has been available since 1959 and remains an affordable and effective medication option added to a full lifestyle-based weight management plan. In people who are generally healthy and without contraindications to the medication, I have had patients used in at least intermittently for sev...