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Geriatric Medicine

Geriatric Medicine

Physician insights on aging-related care, polypharmacy management, cognitive decline, and geriatric syndromes.

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In an older adults with dementia-related behavioral symptoms refractory to nonpharmacological management in whom you are starting SSRI, do you ever consider a short course of antipsychotic medication to overlap with the initiation of SSRI while waiting for therapeutic effect?

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Geriatric Medicine · Beth Israel Deaconess Medical Center

The American Geriatric Society recommends that antipsychotics may be considered when behaviors do not respond to non-pharmacological management and the patient is at risk of harming themselves or others. Thereby, it may be reasonable to overlap short-term antipsychotic with SSRI initiation in older ...

In an older adult hospitalized with recurrent falls, weight loss, without clear injuries, but with an inconsistent or difficult-to-reach caregiver, what findings would make you formally report suspected elder neglect and/or abuse?

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Geriatric Medicine · Keck Hospital of USC

I'm so glad that you're thinking about the possibility of abuse/neglect in this scenario! It's important to have it on our differential, or we'll always miss this diagnosis. First, it would be good to see if the patient can explain what is happening and provide contextual information that veers us a...

What is your approach to the use of GLP-1 agonists in older adults with diabetes with or at risk of sarcopenia?

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Geriatric Medicine · University of California, San Francisco

This is an important question to keep an eye on, given the broadening use and effectiveness of GLP-1 agonists for various conditions, especially diabetes, and for weight loss. Unfortunately, as is so often the case, major clinical trials in this area do not reflect the heterogeneity of older adults ...

In light of recent measles outbreaks in the US, would you recommend an MMR booster for immunocompetent patients born before 1957?

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6 Answers

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Infectious Disease · Perelman School of Medicine at the University of Pennsylvania

I would not recommend a measles vaccine for a person born before 1957. This year has been chosen because people before born before 1957 have a very very high likelihood of having had measles because virtually all children got this highly contagious disease. On the other hand, there is no harm to get...

What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?

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Geriatric Medicine · Wake Forest University School of Medicine

Lion's mane is the latest in the ever-evolving list of supplements that have a whiff of animal data, very small human trials, or frankly, anecdotal evidence. A decade ago, it was coconut oil; last week, it was lithium. There will always be suggestions of the benefit of this or that. Currently, there...

How do you counsel older adults regarding the use, dosing, and safety of CBD-containing products for insomnia?

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Geriatric Medicine · David Geffen School of Medicine at UCLA

When counseling older adults on CBD use for insomnia, I usually explain that evidence for safety and effectiveness is limited. Most products are not FDA-approved, and their labeling, purity, and dosing can be inconsistent. It’s important to review the patient’s comorbidities and medications closely,...

In older adults with chronic mild hyponatremia (Na 128–132) attributed to SSRIs but good psychiatric response, do you tolerate persistent hyponatremia, reduce the dose, or switch agents?

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Geriatric Medicine · University of Minnesota

In my practice, I generally tolerate mild hyponatremia, Na>130, if asymptomatic and mood symptoms have good control. If there’s moderate hyponatremia, Na 125-130, I generally consider either changing the dose or the agent. If severe, Na<125, I would change the agent and likely avoid the entire class...

How do you approach the choice of pharmacological therapy when treating insomnia in older adults in the outpatient setting with a high falling risk?

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Geriatric Medicine · Yale University

My approach is to first see if there are non-pharmacologic options to help with sleep - are there behavioral factors to target (e.g., caffeine or alcohol use; inappropriate sleep scheduling or daytime napping), medications that could disrupt sleep-wake schedules, or untreated sleep or mood disorders...

Do you have any pearls for how to manage OSA with CPAP in older adults with cognitive impairment?

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Geriatric Medicine · Yale University

I try to involve a partner or other family member in the process, including getting a sleep study in the first place. If the study shows moderate or severe sleep apnea, especially with substantial oxygen desaturation, I remind the patient and partner that use of CPAP will help the patient's memory. ...

How do you counsel older adults regarding the use of melatonin (dose and timing) for sleep-related problems?

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Geriatric Medicine · Yale University

Melatonin has a weak hypnotic (i.e., sleep-inducing) effect. It helps people to fall asleep but not to stay asleep. It is not effective in people with chronic insomnia, but it is perfectly safe in low doses (i.e., below 10 mg) and can be helpful for occasional problems with falling asleep. For sleep...