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Geriatric Medicine

Geriatric Medicine

Physician insights on aging-related care, polypharmacy management, cognitive decline, and geriatric syndromes.

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What is the next best osteoporosis treatment option for patients who completed 2 years of teriparatide, but has contraindication to bisphosphosnate therapy (e.g. history of atypical femur fracture)?

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Endocrinology · Boston University School of Medicine

I have successfully treated several patients with bisphosphonate-induced subtrochanteric femoral fractures with Forteo. However, before initiating another antiresorptive therapy, I first want to be sure that the Forteo at the desired effect on bone remodeling by increasing both bone formation and bo...

How do you approach the management of newly discovered prediabetes in adults over the age of 65?

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Geriatric Medicine · Massachusetts General Hospital

We know that even at the same given HgA1c, a 90-year-old patient and a 30-year-old patient have different patterns in their day-to-day sugars. The 90-year-old patient will have a wider amplitude of sugars above and below a given average sugar level. Therefore, while a given HgA1c gives us an idea of...

In outpatient primary care settings, would you recommend routinely checking Cystatin-C as a marker of renal function in older adults?

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Geriatric Medicine · David Geffen School of Medicine at UCLA

I probably would not recommend routine Cystatin-C testing for all older adults, but would consider it in certain scenarios where eGFR may be inaccurate or misleading. In geriatrics, sarcopenia and low muscle mass often make serum creatinine a less reliable marker of true kidney function. Cystatin-C ...

When an older adult with multiple comorbidities develops a new, significant functional decline after a hospitalization, how do you decide whether to pursue further diagnostic workup versus accept it as post-hospitalization deconditioning and focus on rehabilitation?

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Geriatric Medicine · Brown University

I try to characterize the nature of the functional decline in a descriptive sense - what has become difficult and why, what are the patient and caregivers experiencing? I think through a differential diagnosis for that, and then I look at the totality of diagnosed problems from the hospitalization a...

What is your approach to deprescribing cholinesterase inhibitors and/or memantine in advancing stages of dementia?

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Geriatric Medicine · Hackensack Meridian School of Medicine

This is an important question, as pill burden does have a negative effect on the quality of life for the patient as well as the care provider. This becomes even more important with patients having dysphagia and or loss of appetite, common symptoms in patients with advanced dementia. It is important ...

How do you discuss the importance of ongoing lifestyle-based interventions when starting a GLP-1 agonist for medically relevant obesity (i.e., with comorbid conditions)?

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Primary Care · Albert Einstein College of Medicine

I discuss the importance of ongoing lifestyle interventions by going back to the primary research for the corresponding GLPs. I point out the fact that in many of the trials, both the control group and the experimental groups would have some form of therapeutic lifestyle change (usually a mix of edu...

What framework or risk assessment tool is most effective in determining surgical or palliative management of acute hip fracture after a fall in an elderly patient with co-morbidities and poor functional status?

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Geriatric Medicine · Brigham and Women's Hospital

I have found the NSQIP calculator to be the most useful in situations of acute hip fractures in elderly patients. In particular, it looks at more than just cardiac risk perioperatively - it examines functional, pulmonary, and ICU risks. They incorporate a number of co-morbidities and functional stat...

How do you approach the use and interpretation of the FDA-approved plasma pTau181 blood test for Alzheimer's disease in a community-dwelling older adult with subjective cognitive complaints and a normal cognitive screen?

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Geriatric Medicine · UCLA Medical Center

I follow current guidelines, which recommend against testing in those without objective cognitive impairment, given the high rate of false positives. Unless the pre-test probability is high, I would not test. That having been said, future developments (such as subQ modes of anti-amyloid Rx, greater ...

Have you used POCUS with color power Doppler to assess blood pressure in a patient whose cuff readings are in doubt?

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Hospital Medicine · Washington State University Floyd College of Medicine

Thank you for bringing up this question, as it focuses on a POCUS topic I often think about. I will split my assessment into two categories: clinical utility and physiologic limitations, with a brief EBM note at the end. Clinical Utility While the referenced study suggests this technique is feasible...

What go-to resources or apps do you recommend for CBT-I for older adults with insomnia?

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Geriatric Medicine · Yale University

A great place to start is at the American Academy of Sleep Medicine's "Insomnia Toolkit for Clinicians". The toolkit provides links for free digital CBTI platforms, as well as other resources for treatment.