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Geriatric Medicine
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Do you still plan to offer tofacitinib to RA patients over 65 if they have one or more additional CV risk factors?
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2 Answers
Mednet Member
Rheumatology · Mayo
I would consider offering tofacitinib (or another JAK inhibitor) to patients over 65 with an additional CV risk factor, but only as a last resort after all other options have been exhausted.
Do you recommend performing cognitive testing in the clinic to determine the blood pressure target in patients 80 years or older?
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1 Answers
Mednet MemberInvited Expert
Nephrology · UAB Medicine
SPRINT-MIND helps to answer this question. The total number of individuals developing dementia (the primary outcome in SPRINT-MIND) was fewer then expected after a median intervention period of only 3.3 years. This made SPRINT-MIND underpowered to detect the effects of intensive BP reduction on deve...