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Geriatric Medicine

Geriatric Medicine

Physician insights on aging-related care, polypharmacy management, cognitive decline, and geriatric syndromes.

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What is your approach to bisphosphonate use in patients with advanced chronic kidney disease and osteoporosis?

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Nephrology · University Of California San Francisco Medical Center At Parnassus

At this point I would use them. I think the most recent data indicates that they are safe and effective in treating osteoporosis in patients with advanced CKD.

When do you consider using aspirin 81 mg PO BID for VTE prophylaxis over other agents in patients with a fracture, considering recent trial data?

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Hospital Medicine · VA Boston Healthcare System

Aspirin for VTE prophylaxis may be reasonable in selected low-risk patients, but many patients undergoing surgery for a fracture are at high risk for VTE. In addition to the METRC trial you cited, another relevant study informing my opinion on this is the CRISTAL trial.In METRC, the mean patient age...

Do you routinely prescribe vitamin D to reduce the risk of fall-related fractures in elderly patients regardless of their serum levels?

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Geriatric Medicine · University Of California (San Francisco)

Right now, the evidence would NOT support daily vitamin D in older adults who are not deficient just for the purposes of fall prevention. Kahwati et al., PMID 33847712However, lots get missed on fall prevention - so be sure to review all risk factors and make a personalized plan (STEADI resources ar...

Do you routinely adjust your interpretation of SLUMS and/or MOCA tests in patients depending on their level of education?

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Geriatric Medicine · University of California San Francisco

I have routinely adjusted the MOCA score based on their educational level. If their educational level is less than 8th grade, I use MOCA Basic for assessment. Personally, I have not used SLUMS for assessment, so I cannot comment on that.

How do you approach treating depressive symptoms in an older adult already taking an SSRI?

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Geriatric Medicine · David Geffen School of Medicine (UCLA)

I would uptitrate first; then consider adding another agent, or switching if appropriate.

What is your approach to deprescribing cholinesterase inhibitors and/or memantine in advancing stages of dementia?

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Geriatric Medicine · Hackensack Meridian School of Medicine

This is an important question, as pill burden does have a negative effect on the quality of life for the patient as well as the care provider. This becomes even more important with patients having dysphagia and or loss of appetite, common symptoms in patients with advanced dementia. It is important ...

What are the best practices for optimizing transitions from hospital to skilled nursing facilities for older adult patients, with specific regard to adapting hospital medication regimens to the skilled nursing facility setting?

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Geriatric Medicine · VA Greater Los Angeles Healthcare System

Medication errors and discrepancies are well known to lead to adverse drug events during transitions of care, as well as rehospitalization. The standard of care that has emerged over the last twenty years or so is rigorous medication reconciliation. Medication reconciliation is defined as comparing ...

What would be your approach to the consideration of the use of antiamyloid monoclonal antibodies for nonamnestic Alzheimer's disease with a positive biomarker for brain amyloid pathology?

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Geriatric Medicine · Johns Hopkins University School of Medicine

Because treatment appropriateness is based on the stage of cognitive impairment, we base our evaluation on whether the patient meets criteria for mild cognitive impairment or early-stage dementia. We do not use cognitive testing cutoffs, even in amnestic Alzheimer's disease, as staging accounts for ...

How do you approach Vitamin D testing and supplementation in older adults following a fragility fracture?

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Geriatric Medicine · Stanford

Current evidence does not consistently support the use of vitamin D supplementation to prevent falls or fractures among community-dwelling older adults (1–3). However, several studies have reported that individuals who experience osteoporotic or fragility fractures are frequently found to be vitamin...

What is your approach to initiation of mirtazapine for appetite stimulation and depression in older adults, both in terms of starting dose and titration?

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Geriatric Medicine · Duke University

I consider initiation of mirtazapine for older adults who could benefit from at least two of the three potential effects of mirtazapine - improvement of mood, appetite, and/or sleep. I always start at a low dose of 7.5 mg nightly, potentially uptitrating to 15 mg nightly after a week or two if the m...