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Hematology
Clinical discussions on blood disorders, coagulation, transfusion medicine, and hematologic malignancies.
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How would you optimally manage a small solitary plasmacytoma of the alveolar ridge, including minimizing the risk of dental toxicity?
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1 Answers
Mednet Member
Radiation Oncology · Duke University Medical Center
The alveolar ridge is an osseous structure (extension of the mandible and maxilla) that houses the sockets of the teeth. Assuming an appropriate work-up demonstrates no evidence of multiple myeloma (bone marrow biopsy, PET-CT/MRI, laboratory work, etc.), a plasmacytoma arising in this region would b...
Is a bone marrow necessary in patient with splenomegaly and polycythemia vera?
1 Answers
Mednet Member
Hematology · UMass Chan Medical School
Yes. Bone marrow is necessary in a patient with polycythemia vera and splenomegaly. There is a possibility of missing ET or associated primary or secondary myelofibrosis. The only way to distinguish between the three bcr-abl negative MPN namely MF, ET, and PV is by performing a bone marrow biopsy an...