Hematology

Obstetrics & Gynecology

Questions discussed in this category

What guides your choice between prophylactic, intermediate, and full therapeutic dosing of enoxaparin in a woman with APLS and prior fetal loss with no hx of thromboembolic disease?

2 Answers available

For patients with a history of pregnancy loss, do you evaluate for PAI-1 polymorphisms as part of a thrombophilia workup?

If positive, do you anticoagulate for subsequent pregnancies?

1 Answer available

How often do you check weight and adjust anticoagulation dosing in pregnancy?

1 Answer available

How would you manage presumed gestational thrombocytopenia with moderate thrombocytopenia for delivery planning?

Platelet counts 50-80k in third trimester, with no obvious other underlying etiology on work up (vWD, TMA, no hx ITP), and no history of bleeding. How...

1 Answer available

What is your goal ferritin level in pregnancy?

ACOG 2021 practice guidelines use ferritin >30 ng/mL.

2 Answers available

In a patient with sickle cell disease on hydroxyurea who is planning to have a family, for how long should they be off the drug before trying to conceive?

1 Answer available

Papers discussed in this category

Journal of the National Medical Association, 2009-10

Exposure to hydroxyurea and pregnancy outcomes in patients with sickle cell anemia.

Blood,

Reproductive issues in sickle cell disease.

Trials, 2015-05-07

ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial.

Annals of the rheumatic diseases, 2019-10

EULAR recommendations for the management of antiphospholipid syndrome in adults.

BMJ (Clinical research ed.), 1997 Jan 25

Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies).

Arthritis Care Res (Hoboken), 2020 Apr

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Blood advances, 2018-11-27

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.

Lancet (London, England), 2022 Oct 28

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial.

Hematology

Obstetrics & Gynecology

Questions discussed in this category

Papers discussed in this category

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