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Physician discussions on inpatient care, transitions of care, diagnostic reasoning, and hospital-based protocols.

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Should patients who develop primary hyperparathyroidism after 5 years of Prolia treatment for osteoporosis be referred for parathyroidectomy?

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Endocrinology · Bellevue Endocrine Consultants Llc

There are other reasons to treat primary hyperparathyroidism surgically beyond osteoporosis, what is response to treat as far as BMD?

In which patients with nephrocalcinosis and an incomplete distal RTA would you consider further testing for medullary sponge kidney?

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Nephrology · Mayo Clinic

Yes, definitely. The better question is how to test. Since sponge kidney is an anatomical disorder of dilated collecting ducts in the renal papillae, it's best to look anatomically. These are 3-dimensional structures and are best seen with a 3-dimensional image. We no longer have intravenous pyelogr...

How would you approach a patient with new temporal headache, temporal artery tenderness and TA biopsy with mild thickening, but normal inflammatory markers?

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Rheumatology · Berkshire Health Systems

Some more information is needed. Is this bilateral or unilateral and if the latter is there a potential other cause? Was this patient started on prednisone for presumed GCA prior to obtaining the temporal artery biopsy and if so how long before? When were the “inflammatory markers” measured relative...

In which patients with suspected IgA nephropathy and microalbuminuria would you recommend a kidney biopsy?

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Nephrology · Columbia University

There are no guidelines to answer this question. This is my approach. In proteinuric patients, with intact kidney function, threshold proteinuria (UPCR) of 0.5 g/g, or UACR <300 mg/g would be an indication to biopsy. In diseases such as IgA Nephropathy, treatment is driven by the degree of proteinur...

What are the important aspects that you mention when consenting patients for hemodialysis?

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Nephrology · University Of California San Francisco Medical Center At Parnassus

I will answer this question a little differently than I think was the intent of the person asking the question. I find that many patients are resistant to starting dialysis at first. In my first conversation with them, I will make it clear to them that the problem is the kidney failure and not the d...

Is a bone marrow necessary in patient with splenomegaly and polycythemia vera?

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Hematology · UMass Chan Medical School

Yes. Bone marrow is necessary in a patient with polycythemia vera and splenomegaly. There is a possibility of missing ET or associated primary or secondary myelofibrosis. The only way to distinguish between the three bcr-abl negative MPN namely MF, ET, and PV is by performing a bone marrow biopsy an...

Is SVC syndrome a medical emergency?

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Radiation Oncology · Varian Medical Systems/Allegheny health network

It is usually not an emergency but rather a medical urgency and all effort should be made to get a tissue diagnosis before treatment. The goal of treatment could be curative or palliative based on the histology, stage of disease, and performance status of patient

Do you routinely use tumor lysis prophylaxis when starting chemotherapy for germ cell tumors?

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Medical Oncology · Testicular Cancer Commons

THere is not reason to use tumor lysis prophylaxis. Hydration of course is required for the cisplatin. I am not aware of anyone using allopurinol or other TLS approaches

What techniques do you use to treat patients who weigh more than the treatment table limit?

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Radiation Oncology · University of Alabama at Birmingham

In our institutional experience, this weighty question arises more often than we would prefer and most commonly for cervical cancer patients. If the patient is only nominally beyond the limit, it is important to consider that the weight limits are consequent to the tolerance parameters of the motors...

What is your next step in management for a patient with immunotherapy induced pneumonitis that does not improve on high dose steroids for 48 hours?

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Medical Oncology · The Ohio State University School of Medicine

There is an excellent answer to this question from my colleague Dr. @Dr. First Last that can be found here. She provides an overview of the data as well as multiple references.