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Is a bone marrow necessary in patient with splenomegaly and polycythemia vera?

1 Answers

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Hematology · UMass Chan Medical School

Yes. Bone marrow is necessary in a patient with polycythemia vera and splenomegaly. There is a possibility of missing ET or associated primary or secondary myelofibrosis. The only way to distinguish between the three bcr-abl negative MPN namely MF, ET, and PV is by performing a bone marrow biopsy an...

Is SVC syndrome a medical emergency?

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1 Answers

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Radiation Oncology · Varian Medical Systems/Allegheny health network

It is usually not an emergency but rather a medical urgency and all effort should be made to get a tissue diagnosis before treatment. The goal of treatment could be curative or palliative based on the histology, stage of disease, and performance status of patient

Do you routinely use tumor lysis prophylaxis when starting chemotherapy for germ cell tumors?

2 Answers

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Medical Oncology · Testicular Cancer Commons

THere is not reason to use tumor lysis prophylaxis. Hydration of course is required for the cisplatin. I am not aware of anyone using allopurinol or other TLS approaches

What techniques do you use to treat patients who weigh more than the treatment table limit?

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2 Answers

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Radiation Oncology · University of Alabama at Birmingham

In our institutional experience, this weighty question arises more often than we would prefer and most commonly for cervical cancer patients. If the patient is only nominally beyond the limit, it is important to consider that the weight limits are consequent to the tolerance parameters of the motors...

What is your next step in management for a patient with immunotherapy induced pneumonitis that does not improve on high dose steroids for 48 hours?

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1 Answers

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Medical Oncology · The Ohio State University School of Medicine

There is an excellent answer to this question from my colleague Dr. @Dr. First Last that can be found here. She provides an overview of the data as well as multiple references.