Questions discussed in this category
No active joint disease, patient on Hydroxychloroquine and Cimzia. Normal ESR/CRP.
Are these toxicities expected to improve over time?
What would be your RT volumes and dose?
Patient previously trialed two anti-TNFi and Tocilizumab. Avoiding Rituximab due to positive JC virus testing.
Can nodular scleritis be a presenting manifestation of GCA?
Is the diagnosis of Sjogren's mostly clinical in a patient with a consistent history and physical with positive serologies?
And have you ever seen it occur in isolation without any other manifestations of SLE?
The patient has no extraocular features of a spondyloarthropathy and is on methotrexate. No active eye disease for past 1 year.
What is your approach to guiding ophthalmologists regarding our clinical suspicion for ocular syphilis and does the quantification of the titer help i...
If so, when do you recommend timing for the cataract surgery?
Patient is asymptomatic. Labs showed +P-ANCA 1:160. Negative MPO and PR3.
Patient has failed methotrexate and adalimumab.
Patient failed topical ocular therapies, methotrexate, azathioprine.
Is the approach different from uveitis immunosuppression?
Would increased risks from concurrent intravitreal avastin preclude treatment? Would you recommend a waiting period in between the treatments?
Are there specific features that suggest drug-induced uveitis versus de novo uveitis?
Are IL-17 or IL-23 inhibitors helpful?
Patient was previously well controlled on methotrexate, which was discontinued during cancer treatment.
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Papers discussed in this category
Ophthalmology, 2015-05
Retina,
Ophthalmic Res, 2018 Apr 10
Dev Ophthalmol, 2012 Apr 17
Arthritis Rheumatol, 2019 Aug 12
American journal of ophthalmology, 2017-11
Curr Opin Rheumatol,
Annals of the rheumatic diseases, 2012-08
Lupus,
Arthritis Rheumatol, 2020 Jan 07
J Rheumatol, 2013 Nov 15
Arthritis Res Ther, 2005 Mar 01
JAMA Ophthalmol, 2015 Oct
JAMA, 2022 Oct 11
Front Immunol, 2021 May 14
Ophthalmology, 2014-10
Br J Ophthalmol, 2015 Apr 22
Am J Ophthalmol,
Transplant Proc,
Int J Environ Res Public Health, 2021 Aug 01
N Engl J Med, 2021 Jun 23
BMC Rheumatol, 2021 Oct 01
Clin Ophthalmol, 2011 Oct 04
Ophthalmology and therapy, 2023 Aug 21
Journal of the American Academy of Dermatology, 2017 Oct 06
Annals of the rheumatic diseases, 2023 Oct 12
Journal of ophthalmic inflammation and infection, 2015-12
JAMA ophthalmology, 2024 Jan 01
Investigative ophthalmology & visual science, 2016 Feb
Ophthalmology. Retina, 2019 Mar 21
Retina (Philadelphia, Pa.), 2021 Feb 01
Archives of ophthalmology (Chicago, Ill. : 1960), 1995 Dec
The New England journal of medicine, 2016 Sep 15
Arthritis Rheumatol, 2016 Oct 26
Arthritis care & research, 2017 Oct 09
The Journal of rheumatology, 2021 May 01
The British journal of ophthalmology, 1997 Feb