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Palliation

Breast Cancer   

Questions discussed in this category


How, if at all, does your systemic therapy management differ between HER2+ breast cancer patients with active CNS metastases compared to those with stable/treated CNS metastases?
4 Answers available

What is your recommended treatment sequencing strategy in patients with HER2+ breast cancer and leptomeningeal carcinomatosis?
Considering DB-12 study's exclusion of patients with leptomeningeal metastases, can T-DXd still be integrated into treatment plans for these patients?...
3 Answers available

How do you approach breast conserving therapy in a woman who has formed bothersome keloids after prior surgeries?
Is there any alteration in approach from the medical, surgical, or radiation oncology perspective that can mitigate the risk of forming keloids withou...
3 Answers available
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Papers discussed in this category


Nature medicine, 2024 Sep 13
Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial.

Med (New York, N.Y.), 2024 Sep 11
The DEBBRAH trial: Trastuzumab deruxtecan in HER2-positive and HER2-low breast cancer patients with leptomeningeal carcinomatosis.

NPJ breast cancer, 2023 Oct 11
Treatment with trastuzumab deruxtecan in patients with HER2-positive breast cancer and brain metastases and/or leptomeningeal disease (ROSET-BM).

Related Topics in Palliation

  • Lung Cancer
  • Breast Cancer
  • Head and Neck Cancers
  • Hematologic Malignancies
  • Radiation Oncology
  • Gynecologic Oncology
  • Neuro-Oncology
  • Gastrointestinal Cancers
  • Genitourinary Cancers
  • Melanoma/Skin Cancer

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