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Primary Care

Physician perspectives on preventive care, chronic disease management, and evidence-based primary care practice.

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What leads you to suspect that a foot drop is secondary to a myopathy rather than a neuropathic process?

4 Answers

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Neurology · McMaster University

Factors suggesting that a foot drop is due to a myopathy include: Clinical factors (slow progression (myopathy but also seen in CMT) versus acute or sub-acute onset (usually neurogenic), absence of sensory findings, absence of pes cavus, signs of facial or shoulder girdle weakness (FSHD can cause f...

How do you weigh the risks of antipsychotic induced metabolic side effects when treating behavioral symptoms of dementia in a patient with diabetes?

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3 Answers

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Psychiatry · University of Washington

This is an excellent question and is a difficult clinical metabolic risk concern in a poorly characterized population. Most of what we know about antipsychotic-induced metabolic syndrome, such as weight gain, dyslipidemia, insulin resistance, and hyperglycemia, comes from younger patients with schiz...

What is the role for checking uric acid levels in evaluation of SIADH in hospitalized older adults?

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2 Answers

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Nephrology · University of Texas Southwestern Medical School

Uric acid is typically not a first-line test for evaluation of hyponatremia. It's usually used when trying to differentiate between hypovolemic states (not SIADH by definition) and euvolemic states (including SIADH). The utility stems from how uric acid is handled in the nephron, i.e., it's reabsorb...

How do you approach the risk/benefit discussion for IV iron in a patient with concomitant severe iron deficiency and elevated hematocrit due to supra-physiologic testosterone supplementation?

1 Answers

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Hematology · Georgetown University School of Medicine

I only administer iron if symptomatic (pagophagia, RLS, etc). I have not seen iron deficiency with testosterone prior to phlebotomy. When it is required, I literally walk both sides of the aisle. If a non-phlebotomized patient presented with ID, I would work it up like any other. If I have to treat,...

How do you approach the risk/benefit discussion for IV iron in a patient with concomitant severe iron deficiency and elevated hematocrit due to supra-physiologic testosterone supplementation?

1 Answers

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Hematology · Georgetown University School of Medicine

I only administer iron if symptomatic (pagophagia, RLS, etc). I have not seen iron deficiency with testosterone prior to phlebotomy. When it is required, I literally walk both sides of the aisle. If a non-phlebotomized patient presented with ID, I would work it up like any other. If I have to treat,...

For iron deficiency anemia due to heavy menstrual bleeding, what is your preferred method of controlling heavy menses?

3 Answers

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Hematology · The Mass General Porphyria Center

I definitely loop in my GYN friends for this one! According to ACOG: "Heavy menstrual bleeding is defined as excessive menstrual blood loss that interferes with a woman's physical, social, emotional, or material quality of life." The consequences of HMB are substantial and multifaceted, and, as we f...

Do you have any tips for best practices or resources for interacting with adult protective services when reporting elder mistreatment?

1 Answers

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Geriatric Medicine · Keck Hospital of USC

Interacting with Adult Protective Services can sometimes feel like a one-way valve: we make a report, provide information, and don't hear back. I've come to learn that in many jurisdictions, APS is prohibited from sharing information with the reporter, and they actually want to have more/better inte...

How do you approach a patient with IgM monoclonal gammopathy associated with severe neuropathy of unclear etiology?

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2 Answers

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Medical Oncology · University of Kansas Medical Center

I usually confirm if the patient does not have AL Amyloidosis or POEMS, and as part of work up for IgM MGUS, I order MYD 88 mutation. If all are negative and I still believe that neuropathy is caused from his/her MGUS, you can try IVIG for the neuropathy as a trial (of course after using gabapentin,...

Would you order a repeat DEXA scan 1 year later for a kidney transplant patient who had an initial DEXA scan within the first 6 months post-transplant showing osteopenia but no history of fractures, and who has been stable on glucocorticoid-free immunosuppressive therapy?

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Nephrology · UCSF

I agree with Dr. @Dr. First Last. Bone metabolism in renal transplant is woefully shy of good data. My opinion is to monitor Vitamin D levels, provide appropriate supplementation, and monitor PTH levels, using cinacalcet as needed. My target level for PTH is 1-2x the upper limit of normal, also base...

Do you consider using buspirone for the management of anxiety in older patients?

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6 Answers

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Psychiatry · Stanford Medicine Child And Adolescent Psychiatry

While buspirone has been FDA-approved for the treatment of generalized anxiety disorder (GAD) and for short-term relief of anxiety symptoms in general since the 1970s, it is not generally considered a first-line treatment, despite its low misuse potential as a non-benzodiazepine. There are no large ...