Primary Care
Physician perspectives on preventive care, chronic disease management, and evidence-based primary care practice.
Recent Discussions
Would you order a fibroscan to screen for MASLD in patients with insulin resistance but normal LFTs?
Suggest that you check the FIB-4 score first.
In patients with diffuse scleroderma and symptomatic lower extremity venous insufficiency, would you recommend treatment with endovenous laser/ablation?
It all depends on the severity of scleroderma and the severity of the venous insufficiency. No one can give an answer to that without knowing those two things.
Is there any benefit to supervised PAD exercise programs in the presence of collaterals seen on angiography for patients with severe claudication and significant lesions?
Yes, exercise benefits for claudication are more about muscle training and metabolism and general physical conditioning than building of collateral circulation.
What is your approach to the use of Paxlovid for patients with risk factors for severe Covid-19 infection but who have received SARS-CoV-2 vaccines in light of the EPIC-SR trial findings?
Although EPIC-SR Trial may not have shown a significant benefit of paxlovid in standard-risk patients regardless of vaccination status, EPIC HR and real-world evidence have shown benefits in high-risk populations. Shared decision-making with the patient is always the best policy.Disclosure: I have r...
Would you favor stopping low-dose aspirin and continuing OAC alone in a patient with atrial fibrillation and mild coronary artery calcification seen on routine chest imaging?
Absolutely, most of the patients that I would treat with dual-antithrombotics (as opposed to dual antiplatelet plus/minus anticoagulant), have had clinical events. Most commonly MI and/ or stent plus atrial fibrillation. Your patient has one clinical event (AF) and another "subclinical" condition.
How do you evaluate a patient with MGUS and peripheral neuropathy?
When I see a patient with MGUS and peripheral neuropathy, I think about it in stages: Does the patient have an IgM-monoclonal gammopathy? If so, then I think about DADS-M. An EMG/NCS, anti-MAG antibody, PET scan, and bone marrow biopsy are generally all part of the workup. I try to do MYD88 testing...
Is there an age at which you consider not starting antifibrotic therapy in a patient with IPF?
I don't have an age cutoff. In my first couple of years of practice, I was hard-pressed to prescribe octogenarian antifibrotics, but I've come to think that approach is discriminatory.There does not appear to be an age at which antifibrotics lose efficacy. The real question seems to be whether older...
Do you consider administration of nintedanib or pirfenidone via enteral tube in patients unable to take PO due to recurrent aspiration?
I have not ordered nintedanib or pirfenidone via enteral tube for any of my patients. However, in the past, I have looked into it due to some research interests and have discussed it with our local MSLs and our clinical pharmacist. Nintedanib is available only in capsule form and is not recommended ...
Are there any contraindications to starting a patient on Dupixent for prurigo nodularis if the patient is already on Xolair for asthma?
No, and in fact, I have this combination in several patients.
Can combined oral contraceptive use cause falsely elevated 24-hour urine-free cortisol?
UFC is an expression of free cortisol. It should not be affected by oral estrogen.