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Primary Care

Physician perspectives on preventive care, chronic disease management, and evidence-based primary care practice.

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How do you decide between CT and ultrasound imaging tests for surveillance imaging for patients with recurrent nephrolithiasis?

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Nephrology · Mayo Clinic

I much prefer non-contrast renal CT scanning compared to ultrasound to determine metabolic stone activity (an increase in size or number of stones from previous imaging). Although more expensive, radiation exposure is low and sensitivity is high. Determining metabolic activity is important; if activ...

What approaches do you take for your patients with nephrolithiasis who undergo intermittent fasting for cultural, religious, or personal reasons?

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Nephrology · Mayo Clinic

Assuming "fasting" does not prohibit the intake of water, I encourage my patients to continue drinking water frequently, ideally at least 2 L daily, as that is the minimum amount shown in previous studies to decrease kidney stone passage. If fasting is intermittent and includes all fluids, I encoura...

What instances will you start outpatient steroids in patients with nephrotic syndrome of unknown etiology prior to obtaining a kidney biopsy?

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Nephrology · Rush Medical College

It is Friday, your patient presents with classic acute nephrotic syndrome, your biopsy Friday won't have results (if not longer if you need EMs which you need for MCD) until Tuesday. I never think a few days of steroids is a big deal, so I can see doing it.

Are there instances when you recommend femoral vein dialysis catheter placement in patients newly started on hemodialysis in an effort to preserve upper extremity future fistula options?

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Nephrology · University Of California San Francisco Medical Center At Parnassus

I do not recommend tunneled femoral lines for patients who will need dialysis through the catheter for more than a week or so. Temporary femoral catheters are useful at times if unable to place tunneled line expeditiously.

How do you monitor patients with cutaneous lupus for progression to SLE?

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Dermatology · Ohio State University Medical Center

I think it is prudent to check patients with a new diagnosis of cutaneous lupus for any signs of SLE, typically with CBC, CMP, UA, complement levels, and ANA by IFA. If negative, I just screen with review of systems and check labs if something comes up.

How are you navigating approval of CPAP for patients with a high suspicion for OSA on chronic oxygen who are unable to complete an in-lab PSG?

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Pulmonology · Augusta University Medical College Of Georgia

This is a challenging situation for both patient and healthcare provider. The physician is to be applauded for making efforts to get this patient appropriate care despite the very difficult situation to navigate. Of course, the best outcome will occur if we can find a way to get this patient in for ...

What is your approach to use of D-mannose for prevention of recurrent uncomplicated cystitis?

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Infectious Disease · Massachusetts General Hospital

Unfortunately, in light of Hayward et al., PMID 38587819, I think there is a very limited role for the use of D-mannose for the prevention of recurrent uncomplicated cystitis. Our evidence-based options for the prevention of recurrent uncomplicated cystitis in postmenopausal women without catheters ...

What is your approach to determining which patients with ESKD and pruritis should be started on difelikefalin?

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Nephrology · IU Health

Since difelikefalin is a restricted formulary item at my dialysis units, I am required to reserve its use for patients who have failed antihistamines and neuroleptics. If the patient doesn't have traditional Medicare, there may be issues with difelikefalin reimbursement by Medicare Advantage and com...

In patients with Afib on anticoagulation and concurrent intracranial atherosclerotic disease, would you consider adding an anti-platelet to anticoagulation if there are recurrent events that could be related to the ICAD?

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Neurology · Harvard Medical School

This is a difficult clinical situation. If the new stroke was clearly in the vascular territory related to the ICAD, I would consider adding low-dose aspirin to the anticoagulant. I would also consider using the 2.5 mg dose of apixaban as the anticoagulant to reduce the risk of major bleeding associ...

How should we address the questions about the use of hormone replacement therapy in post-menopausal women who have concerns about its relation to breast cancer?

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Medical Oncology · Icahn School of Medicine at Mount Sinai

I am presuming that we are referring to woman that does not have breast cancer. Overall, long term estrogen replacement, especially combined with a progestin, is used much less these days since the Women's Health Initiative trials found an increases in coronary heart disease (CHD), breast cancer, pu...