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Do you routinely prescribe dry powdered inhalers over metered dose inhalers for the purpose of addressing carbon emissions?

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2 Answers

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Hospital Medicine · University of Vermont Medical Center

Appreciate this question because we often forget just how inextricable the link is between human health and climate health. More specifically, carbon emissions from inhalers worsen the respiratory conditions they are intended to treat. Inhaler prescriptions filled by CMS beneficiaries in 2022 were e...

Do you have a preference between an ACEI and ARB when initiating therapy for a patient with diabetic kidney disease, albuminuria, and hypertension?

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7 Answers

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Nephrology · Rush Medical College

Why would you use an ACEi over an ARB these days? Cough is a LOT more common than stated. I see patients all the time who have a ticket, an annoyance that goes away on an ARB. Also, I don't see a $ argument, nor am I aware that ACEi have even been shown to be superior to ARB for reno protection. Als...

What are some practical tips in distinguishing between metabolic bone disease due to chronic kidney disease and osteoporosis?

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Nephrology · U Chicago

The biggest difference between osteoporosis and CKD-MBD has to do with the underlying bone mineral laboratories. Generally, with osteoporosis, bone chemistries are relatively normal; there may be a decrease in Vit D. However, with CKD-MBD, there is usually an increase in PTH, potentially abnormaliti...

Do you use DOAC in patients with mild or moderate rheumatic mitral stenosis?

4 Answers

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Cardiology · Lankenau Heart Group

Although using DOACs in this population may be safe, these patients were excluded from the large DOAC trials. In addition, MS progresses, so what may be moderate disease today will progress rapidly in some patients. Thus, if anticoagulation is necessary and a VKA is a major issue for the patient, a ...

Do you recommend initiating an ACE inhibitor or ARB in a patient with proteinuric CKD Stage 5?

3 Answers

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Nephrology · Los Angeles Vascular Access Center

ACE-I’s and ARB’s have been shown to be renal protective, and patients who have stopped these agents do worse than those who continue them. Potassium binders are an excellent option to lower K levels and enable patients to stay on these RAAS inhibitors. I would not take CKD patients off RAAS inhibit...

What are your recommendations for screening for sleep disorders in patients with IDD?

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Neurology · Virtua Health

Sleep disorders are very common for people with IDD. One consideration, in particular, is in patients with Down Syndrome because of the shape of their mouth and large tongue. They have a very high rate of sleep apnea, obstructive sleep apnea in particular, which can be seen even in children. You wo...

How do you counsel patients on the risks and benefits of antidepressant use during pregnancy?

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Psychiatry · Oregon Health Sciences University

I always frame the decision as being between the risks and benefits of the medication vs. the underlying condition. We are always aiming for the "minimum effective dose" but "effective" is just as important as "minimum." Medications are, of course, not the only way to treat psychiatric illness and a...

How do you counsel patients on the risks and benefits of antidepressant use during pregnancy?

2 Answers

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Psychiatry · Oregon Health Sciences University

I always frame the decision as being between the risks and benefits of the medication vs. the underlying condition. We are always aiming for the "minimum effective dose" but "effective" is just as important as "minimum." Medications are, of course, not the only way to treat psychiatric illness and a...

How do you evaluate and manage incidental urinary retention in hospitalized patients?

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Hospital Medicine · Emory University Hospital

Another great question. First, we need to confirm the presence of urinary retention (>300 ml on postvoid residual [PVR] bladder scan is considered clinically significant to continue evaluating for common reversible causes, such as medications, structural abnormalities, presence of constipation, feca...

Would you recommend initiating a SGLT2i for proteinuria secondary to bevacizumab in a patient who has a sub-optimal response to an ACEi or ARB?

2 Answers

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Nephrology · Yale

We don't have specific data for this scenario, but there is no reason to think that SGLT2i would not have a beneficial role though I agree with Dr. @Dr. First Last that risk/benefit needs to be weighed. At the same time, in this particular scenario, I'd carefully look at the time course of proteinur...