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Physician perspectives on preventive care, chronic disease management, and evidence-based primary care practice.

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When do you recommend neuropsychiatric testing in patients with post-concussive syndrome?

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Neurology · Hartford HealthCare

I typically ask the patient what scenarios they experience cognitive issues. The various examples they provide usually relate to difficulty following conversations, forgetfulness within their working memory, and concentration/focus. In the post-concussion patient, they typically have developed adjus...

What is your approach to the management of patients with recurrent nephrolithiasis who continue to have elevated stone risk parameters in the setting of dietary factors despite receiving education from a dedicated stone clinic dietician?

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Nephrology · Mayo Clinic

Diets are notoriously difficult to follow. Once it is apparent that the patient is not going to get satisfactory control of metabolic stone disease (an increase in stone number or size as opposed to the passage of pre-existing stones, unchanged in size or number), it is time to start preventative me...

How do you approach ADT in patients with high-risk prostate cancer who have risk factors for VTE, such as Factor V Leiden?

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Radiation Oncology

My default recommendation for patients with localized, high-risk prostate cancer is to recommend the use of long-term ADT. This intervention seems to offer a relatively large, clinically significant OS benefit for patients in the modern era receiving dose-escalated ADT. This benefit has been observe...

In what situations would you treat a rectal mass as cancer despite negative biopsies?

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Medical Oncology · Mayo Clinic

It is not uncommon to see a patient with rectal mass highly suspicious for malignancy by endoscopic evaluation but has a negative biopsy. Usually, this is due to superficial biopsy specimens. In our clinic, we usually get repeated endoscopic evaluation with biopsy as our first step. However, a small...

When, if ever, would you consider tapering patients started by another provider on low-dose, as-needed lorazepam for insomnia without a history of cognitive impairment or substance use disorders?

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Geriatric Medicine · Hackensack Meridian School of Medicine

It is important to have a conversation with your patient about potential side effects and benefits of discontinuation of benzodiazepines, especially when it is used for an indication like insomnia. I have had this conversation with any of my patients who are using benzodiazepines. Benzodiazepines ar...

What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?

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Geriatric Medicine · Wake Forest University School of Medicine

Lion's mane is the latest in the ever-evolving list of supplements that have a whiff of animal data, very small human trials, or frankly, anecdotal evidence. A decade ago, it was coconut oil; last week, it was lithium. There will always be suggestions of the benefit of this or that. Currently, there...

What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?

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Geriatric Medicine · Wake Forest University School of Medicine

Lion's mane is the latest in the ever-evolving list of supplements that have a whiff of animal data, very small human trials, or frankly, anecdotal evidence. A decade ago, it was coconut oil; last week, it was lithium. There will always be suggestions of the benefit of this or that. Currently, there...

What therapies do you recommend for patients with recalcitrant seborrheic dermatitis?

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Dermatology · Dermatologists of Central States

Topical roflumilast is easily the most effective thing I've ever seen. Prior to that being available, here were the go-to drugs for difficult seb derm: Itraconazole 200 mg qd until better, then 200 mg qd on weekends long term Fluconazole, exact same regimen if itraconazole not accessible Oral Roflu...

How do you counsel older adults regarding the use, dosing, and safety of CBD-containing products for insomnia?

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Geriatric Medicine · David Geffen School of Medicine at UCLA

When counseling older adults on CBD use for insomnia, I usually explain that evidence for safety and effectiveness is limited. Most products are not FDA-approved, and their labeling, purity, and dosing can be inconsistent. It’s important to review the patient’s comorbidities and medications closely,...

Do you utilize D-dimer to inform anticoagulation duration in the treatment of VTE?

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Hematology · University of Chicago

I had developed a policy during my last eight or ten years of practice evaluating how long patients should be treated after a thrombosis and I'd like to share some impressions over these years as well as conclusions that I reached. These conclusions formed the basis of my approach to this problem. I...