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Did NRG LU004 demonstrate safety with hypofractionated lung radiation and concurrent ICI?

Can you explain the expansion cohorts into larger trials and the current amendments to the the protocol?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Texas MD Anderson Cancer Center
Answered on

We reported the initial safety results at ASCO in 2022 after the trial was completed in 2021. There are no DLT signal and safety concerns of combining durvalumab with radiotherapy, whether it is conventionally fractionated or hypofractionated. The manuscript is under preparation incorporating some b...

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