Do more fractionated regimens reduce severe toxicity over SBRT in patients with ILD and early stage NSCLC?
Answer from: Radiation Oncologist at Community Practice
I personally think fewer fractions are safer, such as 30 Gy x 1 instead of 10 Gy x 5, for patients with advanced COPD or ILD. Why? It's because each time a burst of ionization events is delivered to pulmonary tissues, a wound is created that recruits an inflammatory response that can exacerbate ...