Do oral contraceptives lower bone mineral density in women with hypothalamic amenorrhea by lowering IGF-1?
1 Answers
Mednet Member
Endocrinology · University of Alabama at Birmingham
I am not aware of a well done study in this regard, but oral contraceptives containing estrogen induce growth hormone resistance and may lower IGF-1, but the beneficial effect of estrogen on bone density would almost certainly outweigh any negative effects caused by lowering the IGF-1.