Do you add venetoclax +/- anti CD-20 mAb to a BTKi in patients with CLL who no longer wish to remain on a BTKi many months after starting the BTKi?

What treatment would you recommend to a patient on BTKi for CLL, who no longer wants indefinite therapy with BTKi?

• Continue BTKi, and try to overcome potential reasoning for stopping (cost, side effects, etc)
• No additional therapy until time of next progression/criteria met for treatment
• Venetoclax + anti CD-20 mAb
• Venetoclax monotherapy
• Fixed duration venetoclax + BTKi
• Chemoimmunotherapy
• Other