Do you administer prophylactic antibiotics to prevent VAP following intubation in patients with acute brain injury?
Do the findings of the PROPHY-VAP trial influence your approach?
2 Answers
Mednet MemberInvited Expert
Pulmonology · Emory University Hospital Midtown
Answered on
I currently do not, though this trial is interesting and the results are compelling. I think the risk of one dose of CTX is low. No clear evidence of resistance. I think moving forward, I would have a low threshold for administering one dose of ceftriaxone following intubation in my TBI patients. However, it is unclear how generalizable this would be to other patients such as those with respiratory failure from pneumonia, sepsis, or even CVA.
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Mednet MemberInvited Expert
Pulmonology · Corewell Health
Answered on
No, I don't.
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