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Do you avoid empagliflozin in patients with history of amputation?

We know canagliflozin is not given to patients with amputations, what about other SGLT2 inhibitors
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Do you avoid empagliflozin in patients with history of amputation

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Endocrinology · UNC
Answered on

To be clear, you can prescribe any SGLT2i to a patient with an amputation or at high risk for an amputation due to prior foot ulcers, insensate foot, peripheral vascular disease. The "warning" (not contraindication) in the canagliflozin PI is "Consider factors that may increase the risk of amputatio...

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