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Do you avoid potassium citrate in patients with recurrent nephrolithiasis and hypocitraturia if they also take antihistamine medications?

2 Answers
Mednet Member
Mednet MemberInvited Expert
Nephrology · University of Chicago Medicine
Answered on

I know of no data showing effects of antihistamine meds on urine citrate or on the effects of potassium citrate on urine citrate. I made a Perplexity search which also found no evidence - this is not a topic I have personally researched because I have never encountered clinical issues about it. So -...

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Mednet Member
Mednet Member
Nephrology · WMCHealth
Answered on

Acetazolamide use can make using citrate tricky, and need to watch urine pH and monitor for the development of calcium phosphate stones. The use of citrate can be a double-edged sword in the setting of Acetazolamide use.

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