Do you believe the collective data support neoadjuvant chemotherapy or primary debulking surgery for patients with advanced ovarian cancer?
Given the recent presentation of the TRUST trial results, the benefit of primary debulking surgery seems less clear. What subgroup(s) of patients do you think should undergo primary debulking surgery?
Answer from: at Community Practice
At this time, primary debulking surgery should be applied whenever feasible. However, I think we still do a poor job of selecting patients for PDS versus IDS. We neglect (or do not know) how tumor biology is really affected by surgery. For instance, BRCA-mutated tumors are likely easier to accomplis...