Do you choose an aldosterone synthase inhibitor over other antihypertensives in a patient with HFpEF and uncontrolled hypertension on RAS blockade, given its aldosterone-suppressing mechanism?

Do you choose an aldosterone synthase inhibitor over other antihypertensives in a patient with HFpEF and uncontrolled hypertension on RAS blockade, given its aldosterone-suppressing mechanism?

• Yes, that mechanism alone makes an ASi my preferred add-on antihypertensive in this scenario
• No, I select antihypertensives based on blood pressure lowering efficacy alone
• No, I would not choose an ASi over established antihypertensive options until heart failure-specific outcomes data are available
• I would optimize a non-steroidal MRA before considering an ASi
• Other