Do you consider dual biologic therapy in patients with ABPA that remain steroid dependent despite the use of omalizumab?
Answer from: at Academic Institution
The treatment of ABPA can be so challenging, but this is something that I have not seriously considered at this point. Unfortunately, in general, the evidence for biologics in the treatment of ABPA currently is heterogeneous. Furthermore, many studies are descriptive case reports/series or based on ...
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Answer from: at Academic Institution
Many cases are not always clear-cut ABPA and overlap in the spectrum of eosinophilic asthma; for such patients might be worth switching biologics from omalizumab to another one (which is also more effective for asthma); at least worth a try.