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Do you consider estrogen patches in treatment of prostate cancer?
3 Answers
Mednet Member
Medical Oncology · VCU Massey Comprehensive Cancer Center
Oral estrogenic formulation (such as DES) was historically used for androgen suppression in prostate cancer patients. This was based on the principle that estrogen decreased serum testosterone levels by suppressing luteinizing hormone production through a negative feedback loop on the hypothalamus a...
Mednet Member
Medical Oncology · University of Minnesota–Masonic Cancer Center
No, I have not, and I would advise against it.
Mednet Member
Medical Oncology · Johns Hopkins University
No, I don't. I would not use estrogens in any space. There is plenty of data with estrogens at different doses, routes of administration, various preparations, etc. I don't see any reason to elaborate here, nor do I think it is worth (in my opinion) revisiting this.