Do you consider hyperuricemia as a potential etiology of an anion gap metabolic acidosis in patients with elevated uric acid levels and no other readily explainable causes of acidosis?
Answer from: at Community Practice
Urate has a molecular weight of ~166 mg/mmole and the valence of the anion is -1.
Hence, let us say we have severe hyperuricemia with 16 mg/dl. That will provide an "anion gape" of only 1!
So, by itself, urate cannot increase the anion gap.
Could hyperuricemia be a "biomarker" of other causes of ...
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